Continuous Flow Photo-oxidations Using Supported Photocatalysts on Silica

Vincent Blanchard (1) , Zakariae Asbai (2) , Kevin Cottet (1) , Guillaume Boissonnat (1) , Marc Port (2) , Zacharias Amara (2)

1 Auteur indépendant
2 GBCM - Laboratoire Génomique, bioinformatique et chimie moléculaire

The immobilization of soluble photocatalysts, or photosensitizers, has the potential to reduce the environmental footprint as well as the costs associated with visible-light photochemical processes. We report here on the straightforward preparation of photocatalysts non-covalently supported on silica using electrostatic interactions and compare the activities of these new photocatalytic systems in the photo-oxidation of 1,5-dihydroxynaphthalene to juglone in batch and in a fixed-bed flow reactor. This study demonstrates that simple immobilization strategies can produce stable heterogeneous photocatalysts and provide promising processing options with an up to 24-fold improvement in productivity in flow relative to batch.

Keywords: visible-light photochemistry; photo-oxidation; singlet oxygen; heterogenized catalysts; flow chemistry; juglone

Domains: Chemical Sciences

Vincent Blanchard, Zakariae Asbai, Kevin Cottet, Guillaume Boissonnat, Marc Port, et al.. Continuous Flow Photo-oxidations Using Supported Photocatalysts on Silica. Organic Process Research and Development, 2020, 24 (5), pp.822-826. ⟨10.1021/acs.oprd.9b00420⟩. ⟨hal-03142080⟩