Characterization of Organic Molecules Grafted to Silica or Bismuth Nanoparticles by NMR

Céline Henoumon (1) , Gauthier Hallot (2) , Estelle Lipani (1) , Catherine Gomez (2) , Robert N Muller (1) , Luce Vander Elst (1) , Marc Port (2) , Sophie Laurent (1, 3)

1 NMR Laboratory, Université de Mons
2 GBCM - Laboratoire Génomique, bioinformatique et chimie moléculaire
3 IBMM - CMMI - Center for Microscopy and Molecular Imaging

NMR is a powerful characterization tool and we propose to study the surface of silica or bismuth nanoparticles dedicated to medical applications in order to evidence the covalent grafting of organic molecules on their surface. For that aim, DOSY experiments are particularly useful and allow for the discrimination of molecules interacting strongly with the nanoparticle surface from molecules simply weakly adsorbed at the surface. We were able to characterize thoroughly the surface of different silica and bismuth nanoparticles.

Keywords: nanoparticles surface; DOSY; NMR

Domains: Chemical Sciences

Céline Henoumon, Gauthier Hallot, Estelle Lipani, Catherine Gomez, Robert N Muller, et al.. Characterization of Organic Molecules Grafted to Silica or Bismuth Nanoparticles by NMR. Applied Nano, 2021, ⟨10.3390/applnano2040024⟩. ⟨hal-03414128⟩