Rapid Optimization Using a Design of Experiments Approach: Application to Aluminium-[18F]Fluoride Radiolabeling Method

Carine San (1, 2) , Meriem Beddek (2) , Fabienne Dioury (1) , Nicolas Vignal (2) , Benoit Hosten (2) , Maurice Pillet (3) , Laure Sarda-Mantel (2) , Marc Port (1)

1 GBCM - Laboratoire Génomique, bioinformatique et chimie moléculaire
2 AP-HP. Nord - Université Paris Cité
3 SYMME - Laboratoire SYstèmes et Matériaux pour la MEcatronique

Keywords: Coordination Chemistry; Aluminium; Fluorine 18; Chelating agent; Design of experiments DoE

Domains: Radiochemistry; Organic chemistry; Methodology [stat.ME]

Carine San, Meriem Beddek, Fabienne Dioury, Nicolas Vignal, Benoit Hosten, et al.. Rapid Optimization Using a Design of Experiments Approach: Application to Aluminium-[18F]Fluoride Radiolabeling Method. 29th Young Research Fellows Meeting, Jul 2022, Nantes, France. ⟨hal-03736373⟩